CBC NEWS

World U.S. gov't releases 'playbook' for free COVID-19 vaccines for Americans

1 in 5 Americans say they will not get a coronavirus vaccine shot The Associated Press Posted: 3 Hours Ago 89747046 The U.S. federal government outlined a sweeping plan Wednesday to make vaccines for COVID-19 available for free to all Americans. (David Greedy/Getty Images) Read Comments The U.S. government outlined a sweeping plan Wednesday to make vaccines for COVID-19 available for free to all Americans, even as polls show a strong undercurrent of skepticism rippling across the land. In a report to Congress and an accompanying "playbook" for states and localities, federal health agencies and the Defence Department sketched out complex plans for a vaccination campaign to begin gradually in January or possibly later this year, eventually ramping up to reach any American who wants a shot. The Pentagon is involved with the distribution of vaccines, but civilian health workers will be the ones giving shots. The campaign is "much larger in scope and complexity than seasonal influenza or other previous outbreak-related vaccination responses," said the playbook for states released by the Centers for Disease Control and Prevention. ADV

Among the highlights: For most vaccines, people will need two doses, 21 to 28 days apart. Double-dose vaccines will have to come from the same drug maker. There could be several vaccines from different manufacturers approved and available. Vaccination of the U.S. population won't be a sprint but a marathon. Initially, there may be a limited supply of vaccines available, and the focus will be on protecting health workers, other essential employees, and people in vulnerable groups. CDC's Advisory Committee on Immunization Practices, the National Academy of Medicine, and other organizations are working on priorities for the first phase. A second and third phase would expand vaccination to the entire country. The vaccine itself will be free of charge, and patients won't be charged out of pocket for the administration of shots, thanks to billions of dollars in taxpayer funding approved by Congress and allocated by the Trump administration. States and local communities will need to devise precise plans for receiving and locally distributing vaccines, some of which will require special handling such as refrigeration or freezing. States and cities have a month to submit plans. Researchers look at a sample of a respiratory virus at Novavax labs in Gaithersburg, Md. There is widespread concern that potential coronavirus vaccines are being rushed. (Abdrew Caballero-Reynolds/AFP/Getty Images)

Skepticism over rushed vaccine Some of the broad components of the federal plan have already been discussed, but Wednesday's reports attempt to put the key details into a comprehensive framework. Distribution is happening under the umbrella of Operation Warp Speed, a White House-backed initiative to have millions of doses ready to ship once a vaccine is given what's expected to be an emergency use approval by the Food and Drug Administration. Several formulations are undergoing final trials. But the whole enterprise is facing public skepticism. Only about half of Americans said they'd get vaccinated in an Associated Press poll taken in May. Of those who wouldn't get vaccinated, the overwhelming majority said they were worried about safety. To effectively protect the United States from the coronavirus, experts say upwards of 70 per cent of Americans must either be vaccinated or have their own immunity from fighting off COVID-19. A closer look at the vaccines Canada is betting on to stem the spread of COVID-19 SECOND OPINION What the level of COVID-19 immunity in Canada could mean for the vaccine hunt Since the poll, questions have only mounted about whether the government is trying to rush COVID-19 treatments and vaccines to help U.S. President Donald Trump's re-election chances.  Before the Republican National Convention in August, the FDA granted authorization for treatment of COVID-19 patients with plasma from people who have recovered, even though some government scientists were not convinced the clinical evidence was strong enough. And last week it was reported that Michael Caputo, a Health and Human Services Department political appointee, tried to gain editorial control over a weekly scientific publication from the CDC. U.S. President Donald Trump is hoping a COVID-19 vaccine will increase his re-election chances in the upcoming presidential race. (Mandel Ngan/AFP/Getty Images) As public confidence in core health agencies has taken a beating, Trump administration officials have been forced to play defence. "We are working closely with our state and local public health partners … to ensure that Americans can receive the vaccine as soon as possible and vaccinate with confidence," HHS Secretary Alex Azar said in a statement Wednesday. "Americans should know that the vaccine development process is being driven completely by science and the data." No cause for alarm after pause in COVID-19 trial, says co-chair of Canada's Vaccine Task Force That could be a tough sell. In the AP poll, one in five Americans said they would not get a coronavirus vaccine; 31 per cent said they were unsure. CBC's Journalistic Standards and Practices Report Typo or Error

RELATED STORIES Here's the outlook for COVID-19 vaccines after one late-stage trial was suspended this week Trudeau urges world leaders to pull together as U.S. steers clear of COVID-19 vaccine pledging conference U.S. narrows down candidates in major push for COVID-19 vaccine Your daily guide to the coronavirus outbreak. Get the latest news, tips on prevention and your coronavirus questions answered every evening. Email address: Current Time Ignore this field. If any data is entered for this field, you will not be subscribed to this newsletter. woman files human rights complaint for dress-code discrimination at car dealership 3147 reading now Ontario reports 315 new COVID-19 cases, will lower limits on gatherings in some regions 1188 reading now 23 new cases of COVID-19 in Manitoba, as tally rises again at John Pritchard school 1009 reading now It's easy to point the finger at parties — but younger Canadians spread COVID-19 in all kinds of settings 704 reading now Toronto murder victim dodged earlier assassin's bullet with cocaine bribe COMMENTS To encourage thoughtful and respectful conversations, first and last names will appear with each submission to CBC/Radio-Canada's online communities (except in children and youth-oriented communities). Pseudonyms will no longer be permitted. By submitting a comment, you accept that CBC has the right to reproduce and publish that comment in whole or in part, in any manner CBC chooses. Please note that CBC does not endorse the opinions expressed in comments. Comments on this story are moderated according to our Submission Guidelines. Comments are welcome while open. We reserve the right to close comments at any time. Leave a comment DISCOVER MORE FROM CBC LISTEN 'More than just a blip': Canada's COVID-19 cases on the rise Radio - Front Burner UPDATED Ontario reports 315 new COVID-19 cases, will lower limits on gatherings in some regions News - Canada - Toronto Toronto murder victim dodged earlier assassin's bullet with cocaine bribe News - Canada - Toronto Lawsuit alleges NHL, junior leagues conspiring to limit players' opportunities Sports - Hockey - NHL I'm a gay millennial and I want to be a father — but I can't Parents Pressure mounts on Health Canada to approve rapid COVID testing devices John Paul Tasker News - Politics Fall is the best time to tackle these 6 home improvement projects Life ©2020 CBC/Radio-Canada. All rights reserved

A staggering 50 million Americans deal with long-term ("chronic") pain. Of these people, 20 million have high-impact chronic pain. That's the kind of pain that already interferes with their work, life, and other activities.

So, it's no wonder that chronic pain could be costing the US at least $635 billion each year. That's for the direct costs (e.g., treatment) and indirect expenses (e.g., loss of productivity). However, it doesn't account for the suffering felt by those who always battle it out with pain.

The good news is, CBD oil for pain may help not just with pain, but also its psychological impact. Always being in pain, after all, can raise one's risks for stress and even anxiety and depression.

How exactly does CBD oil help ease pain, though? How does it work, and what types of conditions can it help with?

We've rounded up the most critical facts you need to know, so be sure to read on!

How CBD Oil for Pain Works

Many of the studies on CBD show that it is analgesic and anti-inflammatory. These are the two key reasons for the use of CBD oil for arthritis and other inflammatory conditions.

Moreover, cannabidiol has analgesic properties delivered "without the high." This is one of CBD's benefits that drives people to choose it over pain-relieving drugs.

Pain Relief Through Analgesia

Analgesics are substances that reduce pain without causing a loss of consciousness. They are agents used to relieve pain, be it acute or chronic pain.

In the US, some of the most common analgesics are pharmaceutical drugs. These include nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen. There are also the more potent ones, which include narcotics like morphine.

As helpful as these medications are, many of them come with a high risk of abuse. That's because a lot of them use opioids, which are addictive substances. Yes, we're talking about the same class of drugs that claim 128 lives in the US every day due to overdose.

With that said, it's no wonder that many are turning to cannabidiol, which comes from plants. Indeed, pain-relief is one of the main reasons people buy CBD oil products. One of the biggest reasons for its use is its analgesic properties.

As a pain-reliever, CBD oil extracts can help ease both acute and chronic pain symptoms. Be it neuropathic, back, or muscle pain, CBD seems to help reduce their severity and frequency.

Reduced Pain Through Inhibiting Inflammation

Many people use anti-inflammatory drugs, like NSAIDs, to find relief from pain. Being anti-inflammatory means that something can reduce swelling or "inflammation." Inflammation, in turn, can cause pain, especially if the swelling hits the nerves.

Granted, NSAIDs are "non-habit forming," which means that they have a lower risk of abuse. However, it's also because of this that a lot of people turn to them for pain. The US alone sells over 30 billion over-the-counter NSAIDs every year.

NSAIDs are still drugs, so they always carry the risk of adverse effects. They have shown to raise the odds of intestinal disorders, peptic ulcers, and even strokes.

That's why the long-term use of anti-inflammatory drugs isn't a good idea.

This is where cannabidiol, as a plant-based product, once again comes into play. Studies have found CBD to exhibit anti-inflammatory properties. By reducing swelling, it can also help prevent pain, or at least lessen its intensity.

The Anti-Pain Mechanism of Cannabidiol

Scientists are still studying how exactly CBD relieves pain and swelling. Current literature, however, suggests that it does so by affecting certain bodily processes. These include how the body produces, regulates, and reacts to pain.

Nerve Pathway Interactions

Researchers say that CBD combats pain by interacting with nerve pathways. Cannabidiol appears to disrupt how these pathways send and receive pain signals. By interfering with these signals, CBD seems to dampen the intensity of pain.

Effects On Anandamide

CBD also seems to affect how the body absorbs anandamide. This is a fatty acid neurotransmitter associated with pain regulation. Cannabidiol has shown to stop the process of anandamide absorption.

By preventing the body from absorbing anandamide, more of it stays in the bloodstream. This, in turn, may then lead to a decreased pain intensity.

Endocannabinoid Deficiency

There's also a theory that some people have an endocannabinoid deficiency. Scientists say that this can occur if the endocannabinoid system lacks certain endocannabinoids. If this happens, the body will have a hard time achieving homeostasis.

The endocannabinoid system, after all, is integral in many physiological processes. The ECS, for instance, has regulatory effects on sleep, appetite, mood, and stress, to name a few. It also helps keep the body's immune system functioning correctly.

So, if the endocannabinoid system becomes deficient, the body will become "out-of-balance." One way that this may become more evident is the appearance of pain conditions. Without a fully-functional ECS, you may feel more frequent or severe bouts of pain.

As such, supplementing with CBD products may help offset ECS deficiency. By supplying the body with enough cannabidiol, it may help restore homeostasis.

CBD Oil for Arthritis

Arthritis causes the joints to swell, become tender, and in most cases, feel stiff and painful. Osteoarthritis (OA) is among the most common types of arthritis in the US. OA is often associated with age, and it does worsen as one gets older.

OA causes the cartilage to break down. The cartilage is the hard but slippery tissue found at the end of the bones, by the joints.

The thing is, it's the cartilage that protects the ends of the bones as they move. It serves as a lubricated surface that allows for the least impact on the bones and nerves.

So, when the cartilage breaks down, pain, stiffness, swelling, and immobility follows. In many cases, these symptoms are more evident after rigorous activity. They also tend to worsen during the icy winter season.

Great news, then, as CBD's analgesic and anti-inflammatory effects can relieve arthritic pain. In one study, transdermal (topical) CBD reduced arthritis-caused inflammation and pain. Moreover, the researchers found that cannabidiol didn't have adverse side effects.

CBD Oil for Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation. In people with RA, their immune system launches an "erroneous" attack on healthy cells. This causes pain in the parts of the body mistakenly attacked by the immune system.

As with other types of arthritis, RA is also more common in the joints. In an RA-affected joint, the lining swells, further causing joint tissue damage. The damage itself can be chronic, and can also lead to joint deformity.

CBD, with its innate anti-inflammatory and pain-relieving effects, can help ease RA signs. Also, compared to vitamin C and E, CBD has greater antioxidant activity. While it won't cure autoimmune diseases, it may help boost your overall immune system.

CBD Oil for Inflammation

Aside from OA and RA, CBD can also be helpful for other inflammatory maladies. For instance, it appears to help reduce the severity of acne. This seems to be a result of CBD's anti-inflammatory and anti-microbial activities.

Scientists also found that CBD may help with pancreatic inflammation and diabetes. They found that CBD reduced swelling in the pancreas and also delayed the onset of diabetes. They also discovered that CBD treatment could reduce immune-cell activity.

CBD for Fibromyalgia Pain

Fibromyalgia is a debilitating pain condition that causes widespread body pain. The pain can be so severe that those with this disorder also often develop mood and sleep problems. The constant battle with pain also renders them tired or fatigued for long periods.

In some cases, fibromyalgia may also induce memory problems. Referred to as "fibro fog," these are cognitive issues that appear with fibromyalgia. The symptoms vary, but most experience confusion, impaired thinking, or forgetfulness.

Fibromyalgia also seems to invoke allodynia, which is a heightened sensitivity to pain. It amplifies the pain that one feels, even if it isn't that painful to others who don't have the condition.

One study looked at the effects of THC- and CBD-rich strains on people with fibromyalgia. At the beginning of the study, 52.5% of the patients had a high level of pain. After six months, this dropped to a considerable 7.9%.

Overall, the majority of the participants reported a significant reduction in their pain. What's more, 73.4% of patients said they slept better, and 13.2% even said that their sleep issues went away! Depression-related symptoms also improved in 80.8% of the fibromyalgia patients.

Another study suggested that CBD has a diminishing effect on brain cells known as "glia." These are cells that contribute to central sensitization. Central sensitization, in turn, is a significant component of fibromyalgia.

In this way, high-quality CBD oil products may help provide relief from fibromyalgia.

CBD Offers a More Natural Way To Help Ease Pain

As you can see, CBD oil for pain can bring relief from highly unpleasant sensations. It can also help your joints become mobile once again. Moreover, it can help improve other inflammatory conditions that you may already have.

Best of all, CBD products, like oils, tinctures, and creams, are hemp-based treatments. That makes them a more natural alternative to pharmaceuticals.

If you're looking for CBD products in Minnesota and you need them now, Nothing But Hemp can help. We offer same-day delivery, so you can get your items the same day you place your order.